Research Scientist

Overview:

Senior Research Scientist opportunities are immediately available within the Advanced Center for Translational Genetic Medicine (ACT-GeM) within the Stanley Manne Children's Research Institute. Candidates will be considered for leadership roles for a wide range of interdisciplinary projects with readily available funding. The ideal candidates will be accomplished, highly motivated, and creative scientists with interests in at least one of the three following areas: 1) understanding the architecture of human genetic disease; 2) investigating the mechanisms underlying disease processes; and 3) identification of novel therapeutic paradigms for inherited disorders. Candidates will have the opportunity to work with talented trainees and staff utilizing unique pediatric cohorts; cell-based, zebrafish and/or mouse models; and cutting-edge molecular and imaging technologies in a state-of-the-art facility.

Responsibilities:

Lead and manage project teams to perform experimental design, appropriate literature review, and synthesis of project goals and timelines.Independently perform various laboratory procedures, including cloning, plasmid construction, site directed mutagenesis, microscopy, DNA, RNA and protein isolation and manipulation, RT-PCR, DNA sequencing, and cell culture. May develop own specific project and/or protocols of specific research interest and within focus of the laboratory.

Train staff members on laboratory techniques, Standard Operating Procedures, and equipment specific requirements. Candidates will train new staff on modules including zebrafish embryo manipulation; molecular biology and cloning; PCR and sequencing; immunostaining and microscopy; and tissue culture.

Communicate the results of the study work to the general scientific community through publications and/or oral presentations.

Maintain accurate research records and presents data in group settings.

Collaborate with faculty and trainees in the preparation of manuscripts.

Assist the PI with in development of grant proposals.

Perform other job functions as assigned.

Qualifications:

Ph.D. in a basic or health science. MD or DDS also acceptable. 5 years of postdoctoral experience required.

Previous experience in genetics; cell, molecular, or computational biology; botany; zoology or other directly related scientific fields are required.

Excellent written and oral communication skills, with demonstrated competency in the English language.

Ability to work in a highly collaborative fast-paced environment.

Ability to successfully interact with diverse stakeholders including: clinicians, basic scientists, and translational researchers.

Ability to multitask and manage multiple ongoing projects simultaneously.

Ability to work independently and as part of a team.