Associate Director / Sr Principal Scientist, Biology
Gossamer Bio is a clinical-stage biopharmaceutical company focused on discovering, acquiring, developing and commercializing therapeutics in the disease areas of immunology, inflammation and oncology. Our goal is to create a business that allows value creation and capture at the individual asset level, long-term sustainability, and continuity, while ultimately helping to improve the lives of patients. Job Summary
This position will provide strategic leadership as part of Gossamer Bio research team. The ideal candidate should have a passion for science and medicine, and a track-record of identifying and progressing novel targets to clinical candidates. As a creative scientist and critical thinker, this leader should have a deep understanding of biology with an emphasis on immunology, with a track record of defining key experiments and developing robust and relevant assays to rapidly drive programs to go/no go decision points. We are looking for individuals who embrace our core values of putting people and patients first, in a collaborative team environment that encourages growth and learning. Essential Duties and Responsibilities
- Support the drug discovery process, from target identification and validation through development of drug candidates for clinical development.
- Define and implement key experiments at the forefront of modern biology in the field of immunology and immuno-oncology
- Jointly lead our discovery process and work collaboratively with Chemistry, DMPK, In vivo Pharmacology, Preclinical Development, Translational, Clinical and Regulatory Departments.
- Apply the understanding of pharmacokinetics, pharmacodynamics, in vivo immune cell profiling, and integrate PK/PD/efficacy data to drive drug candidate optimization
- Independently develop and design novel experimental approaches
- Define and develop appropriate in vitro assays to support drug discovery and translation ideally for a diverse set of target classes to include enzymes, GPCRs, transporters, etc.
- Effectively manage and mentor direct reports and other team members.
- Excel in a collaborative multidisciplinary environment, in addition to having excellent written and oral communication skills.
SPECIAL WORKING CONDITIONS
- PhD degree in a Biology or a related relevant scientific discipline and a minimum of 10-12 years of industrial experience with a significant portion of that experience in in vitro pharmacology with an emphasis on Immunology and related fields (inflammation, autoimmune, immuno-oncology and the tumor microenvironment).
- Proven track-record of achievement, as evidenced by publications in peer-reviewed journals, authorship of patents, and internal and/or external scientific presentations.
- Proven ability to lead matrix teams, with demonstrated ability to influence team direction, manage conflict and resolve issues.
- Have excellent written and oral communication skills in order to provide frequent feedback to supervisor, team and governance bodies
- Possess a high level of critical scientific thinking, high energy, independence, a strong desire to learn new areas, and the ability to work in a highly dynamic flexible team-oriented and transparent research organization.
Office environment / Domestic and International travel up to 25% may be necessary
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