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Senior Research Assistant II/Lab Manager (Vascular Cell Biology)

Employer
Joslin Diabetes
Location
Boston, Massachusetts, US
Salary
Competitive
Closing date
Sep 26, 2021

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Sector
Academic / Research
Field
Conservation science
Discipline
Biology
Salary Type
Salary
Employment Type
Full time
Overview:

We are seeking a Senior Research Assistant II who is experienced, organized, and motivated individual to join a lab doing cutting edge basic and translational studies of diabetes and its complications. The successful candidate should have a background in physiology, metabolism, molecular biology, cell biology, or ideally a combination of these areas.

Work in the lab uses cell biological, genetic, biochemical, and physiological approaches to elucidate mechanisms through which abnormal levels of metabolites alter cell physiology and lead to organ damage. Current areas of focus include non-canonical functions of small nucleolar RNAs (snoRNAs), regulated RNA degradation, and translational regulation in response to metabolic stress. Our goal is to discover fundamental mechanisms of metabolic stress responses and to translate our findings in ways that inform development of approaches to improve the lives of patients with metabolic diseases.

Responsibilities:

General laboratory procedures and laboratory management, including assisting in the maintenance of laboratory equipment, ordering supplies, and orientation and training of new personnel.

Maintain and organize lab records and reagent storage.

Regularly communicate with the Joslin Safety Office to ensure compliance with all Safety protocols and COMS (Committee on Microbiological Safety) registrations.

Design, performs and analyzes experiments in collaboration with the Principal Investigator. Reports on data in laboratory meetings.

Adept at biochemical assays and manipulation of DNA, RNA and proteins.

Adept at cell culture and cell based assays

Experience and comfort in handling mice and maintenance of transgenic animal colonies, including genotyping and tissue collection.

Maintain a clearly written and organized experimental electronic notebook.

Work collaboratively with others in the coordination of various projects.

Effectively organize work schedule to accomplish the completion of multiple tasks or multiple experimental procedures.

Qualifications:

B.S./B.A. in Biological Sciences, Biochemistry, Chemistry

Master's Degree or higher preferred

Minimum 5 years of demonstrated practical experience with relevant laboratory methods

Experience with cell culture and molecular biology techniques

Experience handling mice and maintaining genetically modified mouse lines

Attention to detail and ability to concentrate on tasks

Outstanding organizational skills

The ability to work both independently and collaboratively with other members of the team

Good communication skills (written and verbal)

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