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Research Associate, Biology

Company: Kezar Life Sciences
Location: South San Francisco, CA
Employment Type: Full Time
Date Posted: 08/20/2021
Expire Date: 10/20/2021
Job Categories: Biotechnology and Pharmaceutical

Job Description

Research Associate, Biology
Kezar Life Sciences (NASDAQ: KZR), a clinical stage biopharmaceutical company located in South San Francisco, is seeking a Research Associate to join our Biology team. The Research Associate will report to the Scientist, Biology and the position will be responsible for performing high-quality in vitro cell culture and related techniques to support assay development and cell-based mechanism of action studies to characterize novel therapeutic agents. In addition, this position will contribute to novel target discovery and validation of high throughput screening hits through various molecular biology based techniques. Meticulous understanding and execution of developed protocols will be key, as well as enthusiasm for improving processes and interactions within cross-disciplinary teams. The candidate must have excellent problem solving, multitasking, and communication skills.

Kezar is focused on small molecule drug discovery and development to target immune-mediated diseases and cancer. Kezar's lead product candidate, KZR-616, a selective inhibitor of the immunoproteasome, is being evaluated in Phase 2 clinical trials for the treatment of severe autoimmune diseases. KZR-261, Kezar's first oncology candidate targeting the protein secretion pathway via the Sec61 translocon, is entering Phase 1 clinical trials in several oncology indications.

Requirements

- BS degree in cell biology, biochemistry, molecular biology, or related area.
- Previous laboratory experience (1-2+ years) is required (industry setting preferred).
- Proficiency in mammalian cell culture is required.
- Molecular biology (cloning/DNA and protein sequence analysis/QPCR/CRISPR/etc.) or cell based assay experience is highly desired.
- Proficiency in basic data analysis software (e.g., Microsoft Excel, GraphPad Prism) is required.
- Excellent communication, time-management/organization, and presentation skills are necessary. Contact Information Website: https://apply.workable.com/kezar/j/...
Company Description:
Founded in 2015 and based in South San Francisco, Kezar (pronounced "keys are") Life Sciences is combining courage, conviction and cutting-edge science to develop breakthrough treatments for immune-mediated and oncologic disorders - with the hope of helping people overcome their disease and live a better life. We are pioneering first-in-class, small molecule therapies that harness master regulators of cellular function to inhibit multiple drivers of disease via single, powerful targets. We are translating our innovative research in protein degradation (via immunoproteasome inhibition) and protein secretion (via the Sec61 translocon) to have a significant clinical impact in the most difficult-to-treat diseases.

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