Scientist II, Cell and Molecular Biology

Akebia Therapeutics (located in Cambridge, MA) is engaged in discovering and developing novel small molecule therapies to treat and improve lives of patients with kidney disease.

Required Skills

We are seeking a skilled and motivated Scientist to join the biology group to lead the development and execution of cellular/biochemical assays for evaluating the function, activity, and potency of small molecules to advance research programs towards clinical translation. This is a lab-based, hands-on position for a scientist looking to be an integral part of drug discovery teams, manage research associates and CRO's while delivering high quality data in a time bound manner.

Required Experience

Basic Qualifications:

PhD (0-2 years) or MS (4-6 years)

Preferred Qualifications:

• PhD (0-2 years) or MS (4-6 years) in Cell Biology, Molecular Biology, Immunology, or related field
• Experience in designing, establishing, and executing highly robust, reproducible, and validated bioassays to support lead ID and optimization programs
• Ability to develop assays from methods published in scientific articles or application notes
• Experience with mammalian cell culture, cell-based assays, and biochemical/molecular techniques
• Ability to establish and perform ELISA's, cell/tissue RNA/protein isolation, RT-PCR, HTRF, TR-FRET, reporter cell assays
• Strong data analysis, documentation, and presentation skills
• Excellent communication, multitasking, problem solving and collaboration skills
• Ability to work independently and with a positive attitude in a dynamic, fast-paced, cross-functional team environment and adapt to the changes in discovery program priorities and deadlines
• Experience in biotechnology or pharma industry is preferred.
• Experience with immunology assays highly desirable.
• Familiarity with automated liquid handling systems, plate readers like Envision and ability to miniaturize and automate tasks is preferred
• Familiarity with programs like GraphPad Prism, Electronic Lab Notebook (ELN) is a plus
• Experience with outsourcing preclinical studies including CRO selection and management is preferred

Akebia Therapeutics, Inc. is a fully integrated biopharmaceutical company with the purpose to better the lives of people impacted by kidney disease. The Company was founded in 2007 and is headquartered in Cambridge, Massachusetts. For more information, please visit our website at www.akebia.com.

Akebia is an equal opportunity employer and welcomes all job applicants. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law.

We are seeking a skilled and motivated Scientist to join the biology group to lead the development and execution of cellular/biochemical assays for evaluating the function, activity, and potency of small molecules to advance research programs towards clinical translation. This is a lab-based, hands-on position for a scientist looking to be an integral part of drug discovery teams, manage research associates and CRO's while delivering high quality data in a time bound manner.

Basic Qualifications:

PhD (0-2 years) or MS (4-6 years)

Preferred Qualifications:

• PhD (0-2 years) or MS (4-6 years) in Cell Biology, Molecular Biology, Immunology, or related field
• Experience in designing, establishing, and executing highly robust, reproducible, and validated bioassays to support lead ID and optimization programs
• Ability to develop assays from methods published in scientific articles or application notes
• Experience with mammalian cell culture, cell-based assays, and biochemical/molecular techniques
• Ability to establish and perform ELISA's, cell/tissue RNA/protein isolation, RT-PCR, HTRF, TR-FRET, reporter cell assays
• Strong data analysis, documentation, and presentation skills
• Excellent communication, multitasking, problem solving and collaboration skills
• Ability to work independently and with a positive attitude in a dynamic, fast-paced, cross-functional team environment and adapt to the changes in discovery program priorities and deadlines
• Experience in biotechnology or pharma industry is preferred.
• Experience with immunology assays highly desirable.
• Familiarity with automated liquid handling systems, plate readers like Envision and ability to miniaturize and automate tasks is preferred
• Familiarity with programs like GraphPad Prism, Electronic Lab Notebook (ELN) is a plus
• Experience with outsourcing preclinical studies including CRO selection and management is preferred

Akebia Therapeutics, Inc. is a fully integrated biopharmaceutical company with the purpose to better the lives of people impacted by kidney disease. The Company was founded in 2007 and is headquartered in Cambridge, Massachusetts. For more information, please visit our website at www.akebia.com.

Akebia is an equal opportunity employer and welcomes all job applicants. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law.