Scientist, Cancer Immunotherapy and In Vivo Biology

Omeros Corporation
Seattle, Washington, US
Aug 02, 2021
Sep 09, 2021
Employment Type
Full time
Salary Type
Scientist, Cancer Immunotherapy and In Vivo Biology

Omeros is seeking a Scientist to conduct research on the mechanism-of-action and therapeutic potential of novel cancer immunotherapies, leveraging both in vitro and in vivo models.

Good things are happening at Omeros!

Come join our Omeros Discovery Team!

Who is Omeros?

Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, complement-mediated diseases, disorders of the central nervous system and immune-related diseases, including cancers. In addition to its commercial product OMIDRIA (phenylephrine and ketorolac intraocular solution) 1%/0.3%, Omeros has multiple phase 3 and phase 2 clinical-stage development programs focused on complement-mediated disorders and substance abuse. Omeros also has a diverse group of preclinical programs including GPR174, a novel target in immuno-oncology that modulates a new cancer immunity axis recently discovered by Omeros. Small-molecule inhibitors of GPR174 are part of Omeros' proprietary G proteincoupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and their corresponding compounds. The company also exclusively possesses a novel antibody-generating platform.

What are your job responsibilities?

Work with the Discovery Research team to further our understanding of mechanisms of immune control of tumor growth in mice

Leverage, develop, and execute in vitro systems to evaluate the effects of therapeutic molecules on innate and adaptive immune cell function

Leverage, develop, and execute in vivo models of human and murine tumor growth and anti-tumor immunity

Execute experiments, data analysis, interpretation, and planning both independently and collaboratively, including meticulous record keeping and data management/archiving

Present experimental results at project meetings and scientific conferences

Participate in manuscript and patent writing

Education, Experience, Skills, and Knowledge Required:

A PhD degree

Solid understanding of immunology

Experience with mouse models of tumor immunology and in vitro interrogation of T cell function

Demonstrated success in technical proficiency, scientific creativity, collaboration with others and independent thought.

Demonstrated troubleshooting skills and creativity in optimizing and incorporating new experimental methods

Familiarity with computer applications including word processing, spreadsheets, database management, and presentation software

Excellent interpersonal, written, and verbal communication skills

Behavioral Competencies Required:

Demonstrated ability to build and maintain positive relationships with management, peers, and subordinates

Demonstrated ability to work in a team-oriented, highly motivated environment including the ability to foster collaboration

Demonstrated ability to present scientific results to project teams and management

Ability to handle several priorities simultaneously

Willingness to learn new in vivo and in vitro experimental systems

Other Requirements:

This position may require some work on weekends and holidays

Physical Demands Required:

May encounter prolonged periods of sitting

May work around hazardous material

Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes.

It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to or contact Omeros, asking for Human Resources, at (206) 676-5000