Biologist (Protein and Polymer Chemistry)

Employer
GAP Solutions Inc
Location
Gaithersburg, Maryland, US
Salary
Competitive
Posted
Aug 01, 2021
Closes
Aug 13, 2021
Ref
2351112102
Discipline
Other
Employment Type
Full time
Salary Type
Salary
Position Objective: Provide services as a Biologist in support of the overall functions of the Vaccine Research Center (VRC), Vaccine Production Program (VPP) within the National Institute of Allergy and Infectious Diseases (NIAID).
Duties and Responsibilities:
- Coordinate formulation and stability studies in collaboration with senior personnel.
- Execute studies for the evaluation and development of stable formulations for VRC vaccine and biotherapeutic candidates in collaboration with development teams.
- Independently generate samples for analysis using standard laboratory techniques (buffer prep, dialysis, dilution, etc.)
- Independently analyze samples employing spectroscopic, calorimetric and other instrumentation.
- Develop assays for vaccine and biotherapeutic characterization in collaboration with senior personnel.
- Analyze, collate and interpret data independently and in collaboration with team members.
- Write and review technical reports and protocols documenting formulation, stability and method development studies.
- Present data in small group and department settings.
- Oversee external service and execute routine maintenance and troubleshooting for one or more pieces of laboratory instrumentation.
- Coordinate formulation and stability studies under guidance of lead Formulation Scientist, including internal and interdepartmental activities and oversight of data analysis.
- Collaborate with/design formulation and stability studies, incorporating elements of foundational theory with the lead Formulation Scientist.
- Provide technical guidance and expertise to formulation team members.
- Serve as Subject Matter Expert for one or more analytical and/or theoretical areas relevant to formulation development at the VRC.
Basic Qualifications:
- B.S. in Chemistry, Biochemistry, Chemical Engineering or a related discipline
with minimum 2 years of industry, government or equivalent experience in protein formulation or a related field. OR M.S. in Chemistry, Biochemistry, Chemical Engineering or a related discipline. 1 year of academic, industry, government or equivalent experience in protein formulation or a related field (Master's degree experimental thesis may waive this requirement)
- Experience with protein/polymer spectroscopic, calorimetric or particle sizing analysis (UV-Vis, Fluorescence, Circular Dichroism spectroscopy) and protein biochemistry sample handling and analysis (UF/DF, SDS-PAGE, Western Blot).
- Proficiency with Microsoft Excel, Word and PowerPoint.
- Strong knowledge of protein and/or polymer chemistry theory
Minimum Qualifications:
- Basic knowledge of protein and/or polymer chemistry; understanding of biophysical and bioanalytical properties of proteins a plus.
- Experience with data analysis software a plus (E.g. Excel, Prism, SigmaPlot, etc.).
- Strong understanding of biophysical and bioanalytical properties of proteins and relevant analytical techniques desired
- Experience with biologic stability and/or forced degradation studies desired
- Hand-on laboratory experience with analysis and data interpretation using protein/polymer spectroscopic, calorimetric or particle sizing techniques (E.g. UV-Vis, Fluorescence, Circular Dichroism spectroscopy, DLS, HIAC, DSC, etc.) desired
- Experience with Design of Experiment (DOE) software, design and execution desired
- Ability to communicate effectively, orally and in writing, with non-technical and technical staff
- Detail-oriented and possess strong organizational skills with the ability to prioritize multiple tasks and projects
- Ability to work independently with minimal supervision
*This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required by this position.
To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
GAP Solutions provides reasonable accommodations to qualified individuals with disabilities. If you need an accommodation to apply for a job us at recruiting@gapsi.com . You will need to reference the requisition number of the position in which you are interested. Your message will be routed to the appropriate recruiter who will assist you. Please note, this email address is only to be used for those individuals who need an accommodation to apply for a job. Emails for any other reason or those that do not include a requisition number will not be returned.
GAP Solutions is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to their race, ethnicity, ancestry, color, sex, religion, creed, age, national origin, citizenship status, disability, medical condition, military and veteran status, marital status, sexual orientation or perceived sexual orientation, gender, gender identity, and gender expression, familial status, political affiliation, genetic information, or any other legally protected status or characteristics.
This position is contingent upon contract award.
Requisition ID: 4632