Associate Scientist, Neurobiology

Ovid Therapeutics
Cambridgeport, Massachusetts, US
Jul 28, 2021
Aug 26, 2021
Biology, Genetics
Employment Type
Full time
Salary Type
Direct message the job poster from Ovid Therapeutics

Jennifer Colon
Talent Acquisition Specialist at Ovid Therapeutics

OVID Therapeutics

Ovid Therapeutics Inc. is a New York-based biopharmaceutical company using its BoldMedicineĀ® approach to develop medicines that transform the lives of patients with rare neurological disorders. We believe these disorders represent an attractive area for drug development as the understanding of the underlying biology has grown meaningfully over the last few years and today represents a substantial opportunity medically and commercially. Based on recent scientific advances in genetics and the biological pathways of the brain, we aim to identify, discover and acquire novel compounds for the treatment of rare neurological disorders. We have built a deep knowledge of such disorders, how to treat them and how to develop the clinically meaningful endpoints required for development of a compound in these disorders. We continue to execute on our strategy to build this pipeline by discovering, in-licensing and collaborating with leading biopharmaceutical companies and academic institutions. Ovid's emerging pipeline programs include OV329, a small molecule GABA aminotransferase inhibitor for seizures associated with Tuberous Sclerosis Complex and Infantile Spasms; OV882, a short hairpin RNA therapy approach for Angelman syndrome; OV815, a genetic therapy approach for KIF1A associated neurological disorder; and other non-disclosed research targets.

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Ovid Therapeutics is seeking an Associate Scientist (AS) with experience in neurobiology to join our Research and Early Development (RED) team in Cambridge, MA. The Associate Scientist will play a key role in developing preclinical disease models for the assessment of therapeutic modalities, including small molecule or molecular/genetic therapeutics. Within this function, this individual will support all aspects of drug development- from lead identification through drug product validation. As part of a collaborative team environment, this individual will be a pivotal player in preclinical developments and will report to an Associate Director of Research. The AS will conduct R&D projects on various cell types and molecular systems. The ideal candidate has a background in neurobiology and will deliver reliably and responsibly on independent research initiatives by applying technical proficiency, attention to detail, troubleshooting skills, and the ability to interpret changes in methodological design. S/he will analyze and interpret data and present results to various cross-functional project teams.

  • Hands-on experience performing basic cell and molecular techniques, such as protein extraction, protein gel electrophoresis, western blotting, IHC, qPCR, flow cytometry, and cell imaging.
  • Working knowledge using standardized cell lines, iPSCs and/or primary neuronal cultures models
  • Support laboratory activities by helping maintain lab supplies and general lab functions.
  • Analyze and document experimental data for written or oral presentations
  • Build strong collaborative relationships within research and development team to meet project, departmental, and company goals

  • Bachelor's degree or equivalent degree in Cell Biology, Molecular Biology, Biochemistry, or related discipline.
  • 5+ years laboratory experience
  • Experienced in cell and molecular technologies
  • Excellent written and oral communication skills
  • Strong commitment to quality and accountability
  • Strong organizational and project management skills

  • Master's degree
  • 3+ years of relevant industry experience
  • Oversee non-clinical report generation for ongoing studies and results
  • Experience with data plotting and summarizing software (Excel/GraphPad Prism)