Senior Scientist, Molecular Biology

Flagship Pioneering, Inc.
Cambridge, Massachusetts, US
Jul 27, 2021
Aug 02, 2021
Employment Type
Full time
Salary Type
Flagship Labs 63 Inc. (FL63) is a privately held, well-funded, early-stage platform biotechnology company that is leveraging emerging insights in RNA biology to develop a novel class of human therapeutics.

FL63 was founded by Flagship Pioneering, an innovation enterprise that conceives, resources and grows first-in-category life science companies. The firm's institutional innovation foundry, Flagship Labs, is where teams of scientific entrepreneurs systematically evolve ideas and turn previously undiscovered areas of science into real-world ventures. Flagship has created over 100 scientific ventures resulting in >$19 billion in aggregate value, 500+ issued patents, and >50 clinical trials for novel therapeutic agents. Flagship's portfolio companies include Moderna, Rubius Therapeutics, and Indigo Agriculture.

FL63 is a highly dynamic, entrepreneurial and innovation-driven organization seeking to hire an exceptional scientist to join our growing team. A successful candidate will have a Ph.D. in molecular/RNA biology, or a related field, an additional 3+ years of relevant experience, and a proven track-record of scientific excellence as evidenced by a strong publication and/or patent record. The candidate's career goals, technical skills, and core competencies should be aligned with the description below.

Key Outcomes:
  • Leverage your knowledge in RNA biology, with a focus on mRNA translational control, to contribute novel insights into the on-target/off-target effects of our novel therapeutic modality.
  • Continually improve and execute our proprietary Ribo-seq methodology to contribute to ongoing molecular profiling campaigns in the organization.
  • Work independently and in collaboration with our Computational & Molecular Biology (CMB) Research Informatics teams to critically analyze and visualize relevant data streams to provide novel insights.
  • Communicate your results to cross-functional teams. Develop and advocate for new scientific proposals related to RNA biology and method internalization/development to continually expand scientific knowledge and technical capabilities of the Discovery Platform.
  • Continually cultivate scientific and technical expertise through critical review of the scientific literature and attendance at scientific meetings.

Required Skills:
  • Deep knowledge and experience in Ribo-seq technology or related established/emerging molecular profiling techniques in the field of RNA biology.
  • Working knowledge or exposure to computational biology approaches related to data analysis and visualization of the methods above.
  • Track-record of developing and deploying innovative and robust reporter gene strategies to study mRNA translation or other core RNA biology processes.
  • Excellent communication and presentation skills, with an ability to discuss complex methods and results in a clear and accessible manner for all audiences.

Preferred Skills:
  • Experience or exposure to cutting-edge methods related to studying RNA-Protein interactions (e.g. eCLIP, RIP-seq, etc...) and related computational methods.
  • Exposure working on RNA biology pathways and processes related to diseases and causative disease genes to discovery novel solutions with therapeutic implications and potential.

Core Values:
  • Fast-acting/efficient . Moves quickly and proactively with a strong work ethic to produce high-quality results while fostering a positive work environment. Focuses on key priorities. Demonstrates tenacity and willingness to go the distance to get something done.
  • Integrity. Does not cut corners ethically. Earns trust and maintains confidences. Does what is right not just what is politically expedient. Speaks plainly and truthfully. Follows-through on commitments. Expects a high level of personal performance and team performance.
  • Critical thinking. Learns quickly. Demonstrates ability to proficiently understand new information and independently achieve meaningful outcomes. Able to structure and process qualitative/quantitative data and draw insightful conclusions.
  • Creativity & Innovation . Scientifically curious and bold. Generates new and creative approaches to problem solving. Positive ‘can-do' attitude. Views the toughest challenges as the greatest opportunities for personal growth and company innovation. Able to challenge dogma.
  • Teamwork . Fully engaged in facilitating personal and team success. Reaches out to peers and cooperates with the team to establish an overall collaborative work environment. Often solicits and responds well to constructive feedback. Possesses good written and oral communication skills with the ability to clearly and concisely convey ideas and opinions.
  • Flexibility/adaptability. Adjusts quickly to changing strategic and tactical priorities. Comfortable with ambiguity. Self-starter mentality.
Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, "FSP") do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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