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Scientist I, Cancer Immunotherapy and In Vivo Biology

Employer
Omeros Corporation
Location
Times Square, Washington, US
Salary
Competitive
Closing date
Jul 31, 2021

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Scientist, Cancer Immunotherapy and In Vivo Biology

Omeros is seeking a Scientist to conduct research on the mechanism-of-action and therapeutic potential of novel cancer immunotherapies, leveraging both in vitro and in vivo models.

Good things are happening at Omeros!

Come join our Omeros Discovery Team!

Who is Omeros?

Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, complement-mediated diseases, disorders of the central nervous system and immune-related diseases, including cancers. In addition to its commercial product OMIDRIA (phenylephrine and ketorolac intraocular solution) 1%/0.3%, Omeros has multiple phase 3 and phase 2 clinical-stage development programs focused on complement-mediated disorders and substance abuse. Omeros also has a diverse group of preclinical programs including GPR174, a novel target in immuno-oncology that modulates a new cancer immunity axis recently discovered by Omeros. Small-molecule inhibitors of GPR174 are part of Omeros' proprietary G proteincoupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and their corresponding compounds. The company also exclusively possesses a novel antibody-generating platform.

What are your job responsibilities?

  • Work with the Discovery Research team to further our understanding of mechanisms of immune control of tumor growth in mice
  • Leverage, develop, and execute in vitro systems to evaluate the effects of therapeutic molecules on innate and adaptive immune cell function
  • Leverage, develop, and execute in vivo models of human and murine tumor growth and anti-tumor immunity
  • Execute experiments, data analysis, interpretation, and planning both independently and collaboratively, including meticulous record keeping and data management/archiving
  • Present experimental results at project meetings and scientific conferences
  • Participate in manuscript and patent writing
Education, Experience, Skills, and Knowledge Required:

  • A PhD degree
  • Solid understanding of immunology
  • Experience with mouse models of tumor immunology and in vitro interrogation of T cell function
  • Demonstrated success in technical proficiency, scientific creativity, collaboration with others and independent thought.
  • Demonstrated troubleshooting skills and creativity in optimizing and incorporating new experimental methods
  • Familiarity with computer applications including word processing, spreadsheets, database management, and presentation software
  • Excellent interpersonal, written, and verbal communication skills
Behavioral Competencies Required:

  • Demonstrated ability to build and maintain positive relationships with management, peers, and subordinates
  • Demonstrated ability to work in a team-oriented, highly motivated environment including the ability to foster collaboration
  • Demonstrated ability to present scientific results to project teams and management
  • Ability to handle several priorities simultaneously
  • Willingness to learn new in vivo and in vitro experimental systems
Other Requirements:

  • This position may require some work on weekends and holidays
Physical Demands Required:

  • May encounter prolonged periods of sitting
  • May work around hazardous material
Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes.

It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to hr@omeros.com or contact Omeros, asking for Human Resources, at (206) 676-5000

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