Scientist I - Structural Biologist (req1940)

Employer
Frederick National Laboratory
Location
Frederick County, Maryland, US
Salary
Competitive
Posted
Jul 24, 2021
Closes
Aug 01, 2021
Ref
2317264864
Discipline
Other
Employment Type
Full time
Salary Type
Salary
PROGRAM DESCRIPTION

The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers. In addition, the CRTP hosts the Nanotechnology Characterization Laboratory (NCL) which performs and standardizes preclinical efficacy and toxicity testing of nanoparticles intended for cancer therapeutics and diagnostics, and the Antibody Characterization Lab (ACL) which characterizes monoclonal antibodies or other renewable affinity binding reagents for use in cancer related research. CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise.

KEY ROLES/RESPONSIBILITIES

* Sample preparation and grid optimization of challenging samples for single particle and tomography cryo-EM studies
* Process cryo-EM data using various available software packages
* Keep up to date with developments in the field, proposing and implementing changes as necessary and learning and applying new techniques where appropriate

BASIC QUALIFICATIONS

* Possession of a PhD degree from an accredited college or university according to the Council for Higher Education Accreditation (CHEA) in biochemistry, biophysics or related field or eight (8) years of related experience. Foreign degrees must be evaluated for U.S. equivalency
* Ability to obtain and maintain a security clearance

PREFERRED QUALIFICATIONS

Candidates with these desired skills will be given preferential consideration:

* Experience in structural biology, with emphasis on cryo-EM
* Experience with model building programs
* Strong motivation and ability to learn and practice new concepts/tools/techniques
* Ability to work both independently and collaboratively as a team member

JOB HAZARDS

* This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations
* This position is subject to working with radioactive material and requires to become an approved radiation worker