Research Scientist, Cell Biology

Employer
KITE PHARMA, INC.
Location
California, Maryland, US
Salary
Competitive
Posted
Jul 20, 2021
Closes
Aug 01, 2021
Ref
2312722298
Discipline
Biology
Employment Type
Full time
Salary Type
Salary
Kite is continuing to hire for all open roles. Our interview process may be conducted virtually and some roles will be asked to temporarily work from home. Over the coming weeks and months, we will be implementing a phased approach to bringing employees back to site to ensure the health and safety of our teams. For Current Kite Pharma Employees and Contractors: Please log onto your Internal Career Site to apply for this job. Job Description Kite Pharma, a Gilead company, is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) cell therapies designed to empower the immune system's ability to recognize and kill tumors. Discovery Research is seeking a highly motivated Research Scientist to lead characterization studies that address product efficacy and safety. The successful candidate will report to a Director and will be expected to independently design and perform experiments, organize and analyze results, and communicate and present findings in team meetings. Responsibilities * Execution of cell-based functional and biochemical assays to select candidate molecules for clinical development or support combination strategies to enhance T cell product potency and safety * Experimental design aimed to address basic tumor immunology aspects related to the immunosuppressive tumor microenvironment * Genetic/biochemical manipulation of T cells and evaluation of impact on T cell function * Analyze, organize and communicate results at different research and cross-functional meetings * Plan and effectively execute experiments based on strategy, project timelines and goals * Analyze and present scientific results to the project team in addition to cross-functional and cross-site audiences * Document experimental results to enable subsequent clinical studies and patent applications * May serve as a core team member or leader on a project team * Work effectively with other functions (including Process Development, Translational Medicine, Clinical Development) to ensure alignment cross-functionally * Coordinate tasks across multiple projects, demonstrating prioritization and planning * May mentor junior team members and supervise the work of a research team including, but not limited to, organizing and prioritizing laboratory work and review of generated experimental results Basic Qualifications Advanced scientific degree (i.e. MD, PharmD, PhD) OR Master's Degree and 6+ years of scientific experience OR Bachelor's Degree and 8+ years of scientific experience Preferred Qualifications * Experience designing and developing primary immune cell assays using key immune cell populations * Hands-on expertise in T-cell functional characterization assays including in vitro cxytotoxicity, proliferation, cytokine/chemokine measurements, cell signaling, activation, differentiation and exhaustion * Proficient in cell culture aseptic technique * Experience in viral and non-viral methods of gene transfer * Proficient in multi-parameter flow cytometry (panel design, sample acquisition, data processing) and data analysis (FACSDiva, FlowJo, GraphPad Prism, Excel) * Experience in molecular and cellular biology techniques, including by not limited to: PCR, qPCR, cloning and Western blot * Experience with MSD/ELISA and/or Luminex * Ph.D. degree in biology-related field (immunology, cellular and/or tumor biology or a closely related field) * A strong background in cancer immunotherapy and human immunology, experience working with engineered T cells strongly preferred * Demonstrated independence in experimental design, data analysis, interpretation, and presentation * Maintain a high degree of accuracy and attention to detail * Drive to learn and make a meaningful impact * Comfortable in a fast-paced company environment with minimal direction and able to adjust workload based upon changing priorities * Strong collaboration, excellent interpersonal and communication skills * Experience using both written and verbal communication, including presentations, to communicate results to a diverse cross-functional audience * Strong organizational and record keeping skills * Self-motivated, strong sense of responsibility, and willing to accept temporary responsibilities outside of initial job description Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com. Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma. For jobs in the United States: As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@gilead.com for assistance. For more information about equal employment opportunity protections, please view the 'EEO is the Law' poster. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT PAY TRANSPARENCY NONDISCRIMINATION PROVISION Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion. For Current Kite Pharma Employees and Contractors: Please log onto your Internal Career Site to apply for this job.

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