Principal Scientist, Molecular Biology

Kenilworth, New Jersey, US
Jul 11, 2021
Aug 17, 2021
Biology, Modeling
Employment Type
Full time
Salary Type
Job Description
We are recruiting an Associate Principal Scientist to join the Process Cell Sciences team, helping to advance our Company's biologics and cell/gene therapy pipeline portfolio. The individual will lead a critical functional team covering systems biology, biomarker development, and predictive modeling. Candidate should demonstrate and stay up to date on the knowledge of principles and theories related to genetics, cytogenetics, genomics, transcriptomics, proteomics, single cell analysis and genome editing technologies. Based in New Jersey, the Principal Scientist will operate in a highly collaborative environment, partnering with process development, analytics, regulatory affairs and other groups on site and at our Company's other locations.
Primary Responsibilities:
- Lead the Systems biology and predictive modeling team.
- Serve as the subject matter expert in pipeline programs.
- Interface and collaborate with other functional teams in Discovery, Analytics, Operation, CRO/CMO outsourcing in the planning, execution, and technical troubleshooting.
- Responsible for developing cutting-edge technologies and implementing into platform.
- Manage, train and guide junior team members.
- Responsible for memos, technical reports and relevant sessions of IND filing.
Educational Minimum Requirements:
- PhD in Molecular Biology or related area with a minimum of 5 years of biologics industry or related experience.
Required Experience and Skills:
- Experienced in leading biologics pipeline programs and functional team.
- Strong knowledge and strong record of scientific skills in molecular biology, gene editing, NGS, proteomics and current bioinformatics analysis tools.
- Management and leadership experience.
- Experience in mammalian cell culture.
- Strong attention to detail with the ability to multi-task and handle multiple responsibilities simultaneously.
- Excellent project leadership skills in driving for results and innovation.
Preferred Experience and Skills:
- Experienced in hematopoietic cell culture or iPSC generation.
- Experienced in vector engineering and single cell analysis
- Experienced in protein characterization and structural biology
- Experienced in pathway analysis of transcriptome profile with common analysis tools.
- Experience of database and statistical software (e.g. Excel, Access, JMP)
- Familiar with method of cell count, cell viability measurement, ELISA and FACS staining.
We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we "follow the science" that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.
Who we are ...
We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.
What we look for ...
In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization.
In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
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Current Contingent Workers apply HERE ($4020.htmld)
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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.
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Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
VISA Sponsorship:
Travel Requirements:
No Travel Required
Flexible Work Arrangements:
Not Specified
Not Indicated
Valid Driving License:
Hazardous Material(s):
Number of Openings:
Requisition ID: R128101