Sony Biotechnology Inc., based in San Jose, California, supplies advanced flow cytometry analysis and sorting technology for use in life science research. It markets products to private and public research institutions, pharmaceutical and biotechnology companies, and large medical centers. Over the years, Sony Biotechnology products have received numerous outstanding new product awards as well as technology awards including the Frost & Sullivan Emerging Technology award, and the Milestone Award. To learn more: .
Sony Biotechnology is seeking a Scientist-Biology that will support the research and development activities performed at the Sony Advanced Research Center. The Scientist will support dyes and small molecules conjugations to antibodies. This role will have a focus on operating cytometers, and tasks that support research and development of dyes used in flow cytometry. Critical to this role is technical experience in scientific research, experimental design, and assay development.
Develop methods for biomolecular conjugation, purification, and evaluation
Perform sample preparation, surface and intracellular antibody conjugation screening
Perform validation, QC, and optimization of new reagents, including commercially available antibodies, off-the-shelf kits, and specialized detection reagents
Transfer technology to production by designing and implementing scalable manufacturing processes
Perform cytometer and microscopy daily maintenance, and quality control
Conduct developing research project(s) and follow protocols to ensure accurate and comparable scientific results
Analyze and create reports of cytometric results
Support product demonstration and training conducted by team members as needed
Track stability studies; pooling the samples on time and points for testing
Support lab operations and maintenance activities; this includes maintaining lab stock places orders, managing inventories for laboratory supplies, updating databases for chemical inventories, shipments, raw materials, and lab supplies
Perform other duties as assigned
B.A/B.S. degree in Biology or related field and a minimum of 5 years of related work experience in antibodies conjugation technology and Flow cytometry
Must have experience operating a variety of flow cytometers, troubleshooting panel design, working with antibodies and analyzing flow cytometric results
Demonstrates familiarity with cell biology, cell culture, immunology, and cytometry
Experience with laboratory methods (i.e., ELISA, SDS-Page, Western Blot, Microscopy, Spectroscopy, Immunohistochemistry, FL amplification techniques) and equipment strongly preferred (i.e., centrifuge, incubator, BSL cabinets, fume hoods, spectral analyzers, particle analyzers, microscope, and cameras)
Demonstrates basic competency with microscopes, flow cytometry sorters and analyzers, and third-party software analysis platforms including FCS Express and FlowJo
Experience working with human blood and mouse primary cells, and derived cell culture skills at BSL-II level
Possesses basic knowledge of multi-color flow cytometry - including surface, intra-cytoplasmic, phosphorylated-epitope, and/or intra-nuclear cell staining
Works comfortably in a complex laboratory environment
Must be able to lift at least 20 lbs
Demonstrated team player; collaborative, positive and proactive with constructive attitude towards problem solving
Excellent oral and written communications skills; this includes scientific communication and writing skills
Basic descriptive and statistical data analyses, reduction, and presentation skills.
Ability to prioritize and effectively manage multiple projects with minimal supervision
All candidates must be authorized to work in the United States
Sony is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, sex (including pregnancy), gender, national origin, citizenship, ancestry, age, physical or mental disability, military status, status as a veteran or disabled veteran, sexual orientation, gender identity or expression, marital or family status, genetic information, medical condition, or any other basis protected by applicable federal, state, or local law, ordinance, or regulation.
Disability Accommodation for Applicants to Sony Corporation of America
Sony Corporation of America provides reasonable accommodation for qualified individuals with disabilities and disabled veterans in job application procedures. For reasonable accommodation requests, please contact us by email at or by mail to: Sony Corporation of America, Human Resources Department, 25 Madison Avenue, New York, NY 10010. Please indicate the position you are applying for.
Sony is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, pregnancy, national origin, ancestry, citizenship, age, legally protected physical or mental disability, protected veteran status, status in the U.S. uniformed services, sexual orientation, gender identity or expression, marital status, genetic information or membership in any other legally protected category.