Computational Biologist, Stegmaier Lab

Dana Farber Cancer Institute
Boston, Massachusetts, US
Jul 07, 2021
Aug 01, 2021
Employment Type
Full time
Salary Type
Dana-Farber Cancer Institute is seeking a Computational Biologist to work in the laboratory of Dr. Kimberly Stegmaier, Vice Chair of Research in the Department of Pediatric Oncology. The Steigmaier Lab focuses on the application of functional and chemical genomic and epigenomic approaches to identify new therapeutic targets in childhood cancer. This information is used to develop new therapeutic approaches for cancers affecting children.

The Computational Biologist will interact and collaborate closely with other scientists and computational biologists across the Institute and the Broad Institute of Harvard and MIT with the goal of providing necessary computational support to many ongoing projects.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


Analyze sequencing data, for example from RNAseq and ChIPseq experiments
Deploy existing programs and algorithms to evaluate other experimental data generated in our labs (e.g., drug synergy experiments, chemical screens, CRISPR screens)
Provide support for basic computational tasks in the lab
Document methods for reproducible analysis
Participate in projects to design, build, integrate and maintain software to organize and visualize experimental results, including databases and custom user interfaces
Report data and analytical methods in oral and written formats
Participate in all lab meetings and department meetings at DFCI and Broad Institute


Bachelor's degree required. Master's Degree or PhD in Computer Science, Bioinformatics or related field preferred
Familiarity with coding in R or other data analysis / statistics-based language
Familiarity with coding in Python or other similar scripting language
Experience with big data
Experience with data summary visualization
Effective communication skills
Strong organizational techniques, including the ability to handle a variety of tasks in a fast-paced environment

Preferred, but not required:

Experience in computational biology applications
Experience working in a scientific or medical research setting
Experience with pipeline/workflow management frameworks (e.g., Snakemake)
Familiarity with SQL or other database query language

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

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