Research Associate/Senior Research Associate, Molecular and Vector Biology

4 days left

TCR² Therapeutics
Cambridge, Massachusetts, US
Jul 07, 2021
Aug 01, 2021
Employment Type
Full time
Salary Type
At TCR² Therapeutics Inc, our inclusive and diverse team is passionate about curing cancer. We are a clinical-stage immunotherapy company pioneering the development of novel T cell therapies for the treatment of solid tumors and hematological malignancies. Our lead cell product candidate is currently being studied in a Phase 1/2 trial. Our research efforts focus on broadening our pipeline with a series of next-generation enhancements that may further improve clinical outcomes. We are headquartered in Cambridge, Massachusetts and have a clinical manufacturing facility in Stevenage, UK. This position will be based in Cambridge, MA.

We are growing and are looking for a Research Associate/Senior Research Associate to join the Molecular and Vector Biology core. You will report and work closely with our Scientist and will use molecular cloning techniques for the development and optimization of novel cell therapies for the treatment of cancer. The position represents an excellent growth and learning opportunity to learn new techniques, working closely with an experienced team, in a fast-paced and highly collaborative environment.

  • Execute DNA cloning to generate viral vectors
  • Utilize ddPCR to analyze vector integration levels
  • Demonstrate a willingness to learn and apply new technologies and procedures
  • Support laboratory activities by helping maintain equipment and lab supplies
  • Document and analyze experimental data for written or oral presentations

  • B.S./M.S. degree in molecular and cell biology preferred, with at least 1 year experience in either an academic or industry setting with experience and/or desire to learn the following:
  • Experience in one or more of the following molecular cloning, Isothermal Assembly reaction (NEBuilder, Gibson Assembly), and/or PCR is preferred
  • Experience with ddPCR a plus
  • Ability and/or desire to master DNA assembly software is essential e.g. Geneious, CLC
  • Familiarity with mammalian cell culture, electroporation and transduction is a plus
  • Working knowledge of molecular biological techniques for genetic perturbation (shRNA, CRISPR etc.) is a plus
  • Outstanding communication, critical thinking, organizational skills and attention to detail is essential

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