Scientist, Early target biology

4 days left

Employer
Bristol Myers Squibb
Location
Cambridge, Massachusetts, US
Salary
Competitive
Posted
Jul 01, 2021
Closes
Aug 01, 2021
Ref
2292139507
Discipline
Biology
Employment Type
Full time
Salary Type
Salary
At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.
The Scientist will join the Early Target Biology group at Bristol-Myers Squibb in Cambridge, MA and aide in the advancement of early stage therapeutic targets. The position will utilize and develop cellular biological, genome engineering, and functional genomics to screen and validate tumor intrinsic targets that confer resistance to targeted- and immuno-therapies.
The qualified candidate is a highly motivated, interactive, and creative individual that possesses the ability to work across a highly matrixed environment and aid the advancement of the next wave of targets into preclinical drug development. The candidate will be expected to effectively collaborate with colleagues across Discovery Oncology including the exploratory pharmacology, drug discovery and translational research groups. The successful candidate will demonstrate clear and professional verbal and written communication skills and will be capable of communicating these results across multidisciplinary teams. The position requires the ability to design, iterate, and lead several key project initiatives and demonstrate critical thinking to challenge self and others.
Qualifications and key responsibilities
- A B.S. with a minimum of 7 years of experience, or an M.S. with a minimum of 5 years of academic/industrial experience
- Demonstrated independence in experimental design, execution, data analysis, and troubleshooting is required.
- Strong scientific and hands-on experience using a wide range of cellular and molecular biology techniques, including tissue culture, flow cytometry, western blotting, ELISA, use of genetic perturbation techniques (eg shRNA, CRISPR-mediated genome editing), qRT-PCR, cell proliferation assays, molecular cloning techniques, and lentivirus generation and transduction is a requirement.
- Experience in forward and reverse genetic screening followed by target validation studies to elucidate mechanistic biology and oncogenic SAR is strongly preferred.
- Experience in cancer genome data mining through use of desktop tools/interfaces and public databases (e.g., CBIO, TCGA, CCLE, Genepattern etc) is highly desirable.
- Proficiency in utilizing software such as Graph Pad, Microsoft office etc. for data analysis and figure generation is required.
- Ability to lead, design, and execute on project initiatives and operates to a High Standard. Attention to detail with excellent organizational and record keeping skills is a requirement.
- Excellent interpersonal skills with the ability to interact effectively with people, internally and externally, is required.
- This position is located in Cambridge, MA. There will be less than 10% travel.
Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or any part of the recruitment process direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.
Company: Bristol Myers Squibb
Req Number: R1542967
Updated: 2021-07-27 03:58:36.492 UTC
Location: Cambridge,Massachusetts
Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.

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