Senior Scientist - Molecular Biology

4 days left

Talus Bioscience
Seattle, Washington, US
Jun 24, 2021
Aug 06, 2021
Biology, Statistics
Employment Type
Full time
Salary Type
Talus Bio is an early-stage drug discovery company located in Seattle, WA that works to discover and develop cutting-edge therapeutics for gene regulation.

Role Description

We are seeking a Senior Scientist to join our team in a full-time role. The Senior Scientist will work as part of a small team to deploy our platform to enable drug discovery for gene regulators. We are looking for a scientific leader interested in solving complex biological problems in a fast-paced, innovative, early-stage biotech environment.

  • Design and execution of experiments to discover, validate and understand the mechanism of action for small molecule therapeutics
  • Protein isolation from mammalian cells and peptide preparation for mass spectrometry
  • Design, execution and analysis of genomics, epigenomics and/or transcriptomics experiments
  • Data analysis using bioinformatics software including R and/or Python
  • Conduct independent research and demonstrate scientific leadership within the project team and across departments; Collaborate with all the functions within and outside of Talus to advance our science
  • Accurately document experiments and results in electronic laboratory notebooks in a timely fashion
  • Maintain a safe and productive laboratory environment
  • Prepare and present experimental results, analysis, and plans in R&D meetings


  • The successful candidate will have a PhD with 0-3 or BS/MS degree with 5-7 years of industry experience in pharmaceutical development
  • Familiarity with biochemical and cell-based assay development
  • Familiarity with modern sequencing-based assays including ChIP-seq, ATAC-seq and RNA-seq
  • Strong skills in statistics and data analysis using bioinformatics software including R and/or Python
  • Ability to deliver complex results to teams of diverse scientific backgrounds
  • Ability to work effectively and collaboratively on cross-functional projects teams
  • Excellent oral, presentation, and written communication skills

  • Experience working with shotgun proteomics data
  • Experience with CRISPR or related genome-editing technologies
  • Deep familiarity with cancer biology
  • Experience working in small teams and managing contract research organizations (CROs)

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