Scientist, Molecular Biology

VelocImmune (VI) Next is an innovative technology development group that creates and uses complex mouse models and functional assays to study antibody, oligonucleotide, and cell-based therapies across various therapeutic areas in R&D. We are seeking a motivated scientist who has a strong background in Molecular Biology to work in a highly collaborative research environment to build and improve mouse models and other platforms in support of both basic biology and target discovery efforts. In particular to drive innovative technology development in the areas such as antibody engineering, DNA repair, genomic modification, and crispr screens.
As a Scientist on the VI Next team, a typical day might include:
•Driving the design and execution of genomic editing such as large fragments knock-in and knock-out in bacterial cells, mammalian cell lines and primary cells.
•Driving the design and execution cell based CRISPR screening assays to identify novel targets for cell-based therapies as well as other therapies.
•Leading the creation and optimization of novel technologies to efficiently capture and clone large genomic fragments.
•Contributing to novel drug (format) development by designing, phenotyping, validating and troubleshooting new in vitro and in vivo (mouse) models.
•Analyzing large complex data sets independently or in collaboration with in house bioinformaticians; interpret and summarize key findings
•Managing a team of scientists to create team synergy and to drive research programs.
•Demonstrating excellent presentation and communication skills both internally and externally and productively participate in innovative discussions with senior leadership in our collaborative, cross-functional team environment
This role might be for you if:
•You are highly organized, flexible, and able to coordinate multiple projects independently
•You have strong communication skills, including both written and oral communications
•You have excellent presentation and communication skills
•You are an innovative and inspiring leader who can actively participate in meetings with leadership and can collaborate effectively with external research groups
To be considered for this opportunity you must possess a PhD in molecular biology, genetics or related fields with three plus years postdoctoral and/or industry experience. A strong record of innovation and research accomplishments in genomic engineering, DNA repair, molecular immunology, or related field. Extensive knowledge and experience with handling large genomic DNA fragments, or with large scale CRISPR screening, is required. Experience with animal model construction is preferred. Experience with ex vivo engineering and analysis of primary cells is preferred. Experience with NGS methods and analysis and other high throughput methods preferred. Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or maternity status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.
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