Research Associate, Metabolic Engineering

Employer
LanzaTech, Inc
Location
Skokie, Illinois, US
Salary
Competitive
Posted
Jun 16, 2021
Closes
Jun 21, 2021
Ref
2227372559
Discipline
Climate Change
Employment Type
Full time
Salary Type
Salary
Research Associate, Metabolic Engineering

Mission-driven LanzaTech is a revolutionary solution to climate change, capturing pollution to clean our skies and oceans and create new high value products for a sustainable future. LanzaTech captures pollution to make fuels and chemicals, including sustainable jet fuel and products you use every day. The technology is like retrofitting a brewery onto an emission source like a steel mill or a landfill site, but instead of using sugars and yeast to make beer, pollution is converted by biology to fuels and chemicals! Imagine a day when your plane is powered by recycled emissions, when your yoga pants started life as pollution from a steel mill. This future is possible using LanzaTech technology.
  • 2021 Biofuels Digest #1 Hottest Company in Renewable Fuels, Chemicals & Biomaterials
  • 2020 Biofuels Digest #3 Best Company to work for in the Advanced Bioeconomy
  • 2020 Fast Company World Changing Company
  • 2020 CNBC #43 on Top 50 Disrupter Companies list
  • 2019 Chicago Innovation Awards Winner
  • 2019 Fortune Magazine - Change the World - Companies to watch
  • 2019 Kirkpatrick Chemical Engineering Achievement Award
  • LanzaTech is committed to Diversity, Equity & Inclusion as part of our mission, culture & core values

This position is open to candidates authorized to work in the United States on a full-time basis for any employer. LanzaTech is an Equal Employment Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status.

About the Role

We are seeking a Research Associate to improve laboratory processes and support metabolic engineering and characterization of LanzaTech's proprietary gas fermenting microbes. The Research Associate will be joining LanzaTech's Synthetic Biology team, working in the lab and interacting with other teams across the company. This role will support Senior Scientists on project-based work as well as a variety of lab management tasks. The Research Associate will work towards both specific goals and towards improving workflows to benefit all Synthetic Biology team members. Types of activities include plasmid construction, bacterial transformation and culturing, confirmation of clones, product screening, genetic parts characterization, curating strain and plasmid repositories, preparing buffer and media, stocking consumables, authoring training and protocol documents, etc.

Duties & Responsibilities:
  • Design, cloning and assembly of multi-fragment DNA constructs for heterologous pathway expression
  • Genetic modification and selection of LanzaTech proprietary microbes
  • High-throughput cultivation and screening of LanzaTech proprietary microbes
  • Analysis of data and interpretation of results against model predictions
  • Use of computational tools and databases
  • Learn established workflows and implement improvements
  • Support organization of training, protocol, and other document development
  • Assist in general lab chores such as solution prep, cleaning, organization, etc.
  • Maintain a laboratory notebook, track and QC data in LIMS system as required
  • Attend seminars and participate in group and project meetings and lab activities

Requirements:
  • M.Sc. or B.Sc. (or equivalent) in Synthetic Biology, Bioengineering, Biochemistry, Molecular Biology, Chemical Engineering or a related field with preferable 1-2 years of relevant experience in a laboratory setting
  • Hands-on experience in cloning and assembly of DNA and growth of microbes
  • Use of DNA design software, word processing, data collaboration tools, presentation and spreadsheet applications, and familiarity with concepts in statistics and tools to analyze data
  • Strong organizational, time management, record keeping, and prioritization skills
  • Independent, hard-working, and highly self-motivated
  • Excellent communication and interpersonal relationship skills
  • Ability to maintain a positive attitude when faced with challenges
  • Desire to work in a team and assist other team members
  • Awareness of safety issues in the work environment

Highly preferred:
  • Experience with gas fermentation
  • Experience in biotech industry
  • Experience with metabolic engineering
  • Experience different cloning methods such as Gibson or Golden Gate assembly and genetic tools such as CRISPR and homologous recombination
  • Experience working with genetic and metabolic pathway databases and DNA design software
  • Experience working with anaerobic microbes
  • Strong computer literacy, including Office, SharePoint; Experience in scripting and working with large datasets is preferred
  • Ability to conduct research independently and manage multiple tasks in parallel
Are you authorized to work for any US employer without restriction or need for sponsorship in the next 5 years? *
Are you comfortably able to commute to Skokie or are you willing to relocate to accommodate? *

Do you have an M.Sc. or B.Sc. (or equivalent) in Synthetic Biology, Bioengineering, Biochemistry, Molecular Biology, Chemical Engineering or a related field with preferable 1-2 years of relevant experience in a laboratory setting? *

Do you have hands-on experience in cloning and assembly of DNA and growth of microbes? *

Do you have experience with the use of DNA design software, word processing, data collaboration tools, presentation and spreadsheet applications, and familiarity with concepts in statistics and tools to analyze data? *

Speak to your organizational, time management, record keeping, and prioritization skills. *

Do you have experience with gas fermentation?
(Preferred, not required) *

Do you have experience in the biotech industry?
(Preferred, not required) *

Do you have experience with metabolic engineering?
(Preferred, not required) *

Do you have experience in different cloning methods such as Gibson or Golden Gate assembly and genetic tools such as CRISPR and homologous recombination?
(Preferred, not required) *

Do you have experience working with genetic and metabolic pathway databases and DNA design software?
(Preferred, not required) *

Do you have experience working with anaerobic microbes?
(Preferred, not required) *

Speak to your computer literacy skills, including Office, SharePoint; Experience in scripting and working with large datasets is preferred. *

Speak to your ability to conduct research independently and manage multiple tasks in parallel. *

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