Senior/Principal Data Scientist, Single-cell Biology

Cambridge, Massachusetts, US
Jun 13, 2021
Jul 29, 2021
Employment Type
Full time
Salary Type
Position Overview:

The Single-cell group in the I&I Precision Immunology Cluster at Sanofi is focused on delivering first-in-class medicines to patients by deconstructing the mechanisms of autoimmune disease into cellular building blocks and advancing first-in-class therapeutics for precision targeting of pathogenic cell types. Our efforts have achieved significant internal and external visibility and media presence.

We are seeking a highly competent, independent, proactive, driven and well-organized Principal Data Scientist to build on our present achievements and ensure our future success. The ideal candidate will derive professional satisfaction from:

Applying established single-cell computational workflows to understand disease and drug mechanisms Developing and maintaining cutting-edge expertise on state-of-the-art computational methods for single-cell analysis, keeping up to date with a growing body of literature and judiciously internalizing the best-performing/most useful workflows Leading the development of novel methods and approaches to data integration, target ID, pathway analysis using single-cell and bulk genomic data Transversally leading and contributing to projects involving genomic data analysis focused on specific drug discovery/development programs Collaborating with academic, industry, and internal partners on method development and disease-focused scientific studies. Leading and contributing to high-profile presentations and publications.

S/he will have the ability to independently set up and execute complex workflows, clearly and consistently document results, and establish their relevance to key decision points in the drug discovery process. Opportunities to mentor interns and junior scientists may be available. This is a hands-on data analytics position.

Basic Qualifications:
  • Ph.D. in Computational/Systems Biology or related discipline, with 3+ years of postdoctoral training at a solid academic institution and/or equivalent work experience.
  • Expert coding skills in R and/or python.
  • Extensive knowledge and hands-on experience with advanced single-cell data analysis workflows required (e.g. Seurat, SPRING).
  • Proficiency in working with UNIX, HPC required.
  • Experience with cloud environment preferred.
  • A track record of productivity, innovation and impact (publications, patents).
  • Familiarity with basic principles of single-cell experimental design.
  • Excellent communication, organizational, interpersonal and team skills; track record of success working collaboratively across disciplines.

What we offer:
  • A combination of start-up mindset and big pharma stability.
  • An academic spirit of curiosity and potential for direct impact on people's lives.
  • An environment fostering individual growth, ensuring visibility and celebrating achievement.
  • Flexible, goal-oriented work schedule, and excellent work-life balance, allowing you to thrive both professionally and personally.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.


At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.

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