R&D Specialist (RGC Biology)

The Biology group of the Regeneron Genetics Center (RGC) is looking for a R&D Specialist highly skilled in molecular and cellular biology and immunology. You will be responsible to research projects aiming at the understanding of the mechanistic features of the associations between RGC-identified human gene variants and inflammatory diseases via in vivo and in vitro studies. This work will support the pre-therapeutic pipeline and the target development platforms of THIS ROLE, A TYPICAL DAY MIGHT INCLUDE PERFORMING THE FOLLOWING:

* Apply current state of the art molecular cloning techniques to construct targeting and expression vectors; in vitro engineering of reporter cell lines for characterization of genetic variants; perform transfections/infections, RNA interference and genome editing; dive into mechanistic studies through qRT-PCR and protein techniques such as Western blots and ELISAs, kinase and uptake assays.

* Work with primary cell and organoid cultures and pharmacological treatments.

* Develop new methods and apply troubleshooting tactics when needed.

* Design, execute, and analyze experiments with minimal supervision

* Execute in vivo experiments using mouse models.

THIS JOB MIGHT BE FOR YOU IF:

* You enjoy working productively in a fast-paced collaborative environment.

* You have an eye for detail and pride yourself on the quality of your work.

* With your sleeves rolled up, you work on current problems while thinking of future solutions.

* You have excellent interpersonal, communication and presentation skills.

To be considered for the role, you must have a Master's degree and 3 years' experience or Bachelor's degree in related field and 5 years of hands-on experience with molecular and cellular biology techniques (including DNA cloning, PCR, sequence analysis, protein expression and purification, and western blotting). Experience with primary cell culture and /or organoids and cell-based assays. Experience with CRISPR/Cas9 genome editing, highly desired. Proficiency with microscopy, imaging technologies; FACS, a plus. Experience with mouse experimentation.

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or maternity status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.