Senior Scientist - RNA Biology

4 days left

Employer
Aerotek
Location
Bothell, Washington, US
Salary
Competitive
Posted
Jun 05, 2021
Closes
Jun 19, 2021
Ref
2230723018
Discipline
Biology
Employment Type
Full time
Salary Type
Salary
Description:
Role Description:
We are seeking an experienced and creative leader to join our interdisciplinary R&D team with the focus on product development of therapeutic nucleic acids. This candidate will take the leading role within the R&D group to develop new products and applications. He/she will also drive collaboration and communication with our production team and biologics department.
Key Responsibilities:
• Lead a cross-functional team to propose, design, plan, and manage R&D projects with focus in gene and RNA therapeutics applications
• Develop and optimize large scale DNA and RNA production process
• Lead the research efforts on RNA design, modifications, and protein translation for mRNA and circular RNA.
• Synthesis and characterization of RNA and DNA constructs
• Define QC methods for the developed products/service
• Collaborate with and/or supervise the scientists and engineers on joint projects
• Transfer developed technologies to the production team and provide support as needed for process improvement, scale-up or troubleshooting
• Perform statistical data analysis and present the results
Skills:
rna, rna isolation, rna sequencing software, RNA design, enzymatic assay, RNA assay
Top Skills Details:
rna,rna isolation,rna sequencing software,RNA design,enzymatic assay,RNA assay
Additional Skills & Qualifications:
• Ph.D. in Biochemistry, Molecular Biology, Synthetic Biology, Microbiology, Biomedical Engineering, or related biomedical field with a minimum of 3 year experience in the pharmaceutical company, biotech or related industries
• Proven ability to analyze multi-factorial data, provide conclusions and design next steps independently.
• Knowledgeable in nucleic acid chemistry, molecular/cellular mRNA metabolism and translation mechanism
• Expert in RNA biology and RNA chemistry including structure simulation, design, modification and stability improvement
• Strong molecular biology laboratory skills. Experience in nucleic acid amplification, in vitro transcription, primer/probe/vector design, enzymatic reactions, PCR, qPCR, next-generation sequencing, molecular cloning and large scale plasmid preparation
• Experience in process development for cGMP-compliant therapeutic nucleic acid production is preferred
• Experience in various qualification, quantification, and nucleic acid purification methods, e.g., PCR, qPCR, PAGE, CE, HPLC, UPLC, NGS, etc.
• Experience with automation platforms is a plus
Experience Level:
Expert Level
About Aerotek:
We know that a company's success starts with its employees. We also know that an individual's success starts with the right career opportunity. As a Best of Staffing® Client and Talent leader, Aerotek's people-focused approach yields competitive advantage for our clients and rewarding careers for our contract employees. Since 1983, Aerotek has grown to become a leader in recruiting and staffing services. With more than 250 non-franchised offices, Aerotek's 8,000 internal employees serve more than 300,000 contract employees and 18,000 clients every year. Aerotek is an Allegis Group company, the global leader in talent solutions. Learn more at Aerotek.com.
The company is an equal opportunity employer and will consider all applications without regards to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

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