Associate Director Biology

Employer
WuXi AppTec
Location
East Windsor, New Jersey, US
Salary
Competitive
Posted
Jun 05, 2021
Closes
Jun 13, 2021
Ref
2231102606
Discipline
Biology
Employment Type
Full time
Salary Type
Salary
WuXi AppTec is a leading global pharmaceutical, biopharmaceutical, and medical device open-access capability and technology platform with global operations. We're seeking a Assistant Director for our In-Vitro Biology group located in Cranbury, NJ.

  • Self- Motivated, requires minimal supervision and determines next steps with minimal guidance
  • Performs preliminary lab work independently.
  • Maintains research notebooks in a well-organized manner. All necessary documentation is recorded.
  • Complies with all safety rules, practices good housekeeping, and maintains safe workplace without supervision.
  • Develops new methods or assays based on minimal information or protocols.
  • Makes logical suggestions of likely causes of problems and independently suggests solutions.
  • Adept in operating semi-automated liquid dispensers, plate readers, and other lab instruments
  • Performs routine calculations, tabulates, and records results. Maintains and calibrates laboratory equipment.
  • Assumes responsibility for technical accuracy of work.
  • Demonstrated ability to lead and manage other scientist and associates.
  • Has expert skills in any of the following areas:
  • Must possess prior experience in quantitative workflow development and/or proteomics technology development (LC-MS; ideally on TSQ Altis QQQ, and/or ABSciex 6600+ Triple TOF, Orbitraps)
  • Must be able to prepare samples from tissues, cells, and biofluids as needed to enable quantitative workflows for drug discovery programs
  • Prior experience in PTM analysis (phosphorylation and ubiquitination) and targeted proteomics
  • Experience with MaxQuant, Skyline and Tracefinder, Protein Pilot, Proteome Discoverer is a plus
  • Must be able to maintain UPLC/Mass spec for routine operations
  • Biochemical assays including determination of steady-state kinetic parameters and elucidation of inhibitor/binder mechanism of action.
  • Experience with high-throughput screening (HTS) and small-molecule drug discovery is preferred.
Works on assignments with a diverse team of scientists to facilitate all aspects of performing high-throughput screening and running an HTS laboratoryMakes decisions based on an understanding of client program goals.Communicates frequently with client and provide frequent update reports

Experience / Education
  • Minimum: PhD + 10 or MS degree + 12 or BS degree + 14 years experience in Proteomics, Mass Spectrometry, biophysics and/or plate-based assay development and biological sciences or related field


Knowledge / Skills / Abilities:
  • Ability to think critically and scientifically
  • Able to work in a fast paced environment
  • Ability to search scientific literature and suggest protocols and methods
  • Expert knowledge of commonly used concepts, practices, and procedures within biological R&D laboratory setting
  • Well organized, detail oriented, and adaptable to changes
  • Excellent oral and written communication skills
  • Excellent interpersonal skills
  • Computer skills: knowledge of internet research, MS Word, Excel, Outlook, and PowerPoint. Ability to learn instrument and data analysis software.
  • Good time management and multi-tasking skills in order to complete multiple projects within timelines.
  • Ability to effectively prioritize workload and manage changes in direction
  • Ability to work in a team environment
  • Records experimental procedures and results in notebook
  • Regularly reviews goals and objectives with supervisor
  • Demonstrates competence in relevant technical aspects of scientific discipline which allows for increasing level of independence
  • Demonstrates attention to details and concern for impact


Physical Requirements:
  • Must be able to work in an office environment with minimal noise conditions.
  • Must be able to work in Lab setting with exposure to Animals/biohazards / Chemicals (List specific Chemicals)
  • Must not have animal allergies to applicable species in this facilityMust be able to wear appropriate PPE
  • Must be able to work in environment with variable noise levels
  • Ability to stand /Sit/walk for long periods of time
  • Ability to Lift 10 lbs. routinely
  • Ability to crouch, bend, twist, and reach
  • Ability to push/pull 10 lbs. routinely/ often / occasionally
  • Clarity of Vision
  • Ability to identify and distinguish colors
  • Must be able to perform activities with repetitive motions
  • Ability to climb Ladders / Stairs / Scaffolding
  • Ability to work in variable temperatures high to freezing
  • Inside/outside working conditions

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