Senior Research Associate, Molecular Biology & Genomics

3 days left

Employer
Homology Medicines, Inc.
Location
Bedford, Massachusetts, US
Salary
Competitive
Posted
Jun 05, 2021
Closes
Jun 21, 2021
Ref
1896795702
Discipline
Biology
Employment Type
Full time
Salary Type
Salary
The Senior Research Associate, Molecular Biology & Genomics, is a key member of our Molecular Genomics team, developing advanced genomics technologies to identify and advance rare disease targets for drug discovery and for development. This role is responsible for utilizing a variety of techniques including but not limited to advanced cloning, nucleic acid purification, PCR-based assays, mammalian cell culture, viral preparation and purification, and NGS, to support the Genomics team in executing DNA-based therapy workflow. This organized, self-motivated, detail-oriented, and team-oriented researcher will partner with co-workers, senior experts, and across multiple functions including Discovery Research and Analytical Process Development, to ensure work is completed to support Genomics research.

  • Design and implement experiments, analyze data, and present results to demonstrate feasibility of new methods with the goal of efficiently moving products through our pipeline.
  • Analysis and interpretation of genome-scale data.
  • NGS
  • Advanced cloning, PCR-based assays, and qPCR.
  • Column and solvent-based nucleic acid purification.
  • Mammalian Cell Culture and cell-based assays.
  • Molecular genomic assays evaluating genome-wide editing.
  • DNA/RNA extraction and quantification.
  • Vector design and cloning.
  • Whole-genome viral integration analysis.
  • Gene expression.
  • Expression Cassette design.
  • Maintain expertise in state-of-the-art molecular biology tools and methods.

  • BS or MS degree in Biological Sciences with a minimum of 5 years' relevant, hands-on experience in an academic or biotechnology/pharmaceutical laboratory environment.
  • Organized, self-motivated, detail-oriented, and team-oriented.
  • Demonstrated excellence in communication, organizational, and interpersonal skills are essential.
  • Demonstrated ability to think critically, problem-solve creatively, and to work collaboratively as a member of our fast-paced research team required, and must be able to accommodate rapidly changing priorities and deadlines.
  • Familiarity with robotic liquid handlers, experience with Fluidics and Flow Cytometry, and/or experience with single-cell genomics and Bioengineering a plus.

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