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Research Associate, Biology

Job Description
Research Associate, Biology

Duties and responsibilities

Apply genetic methods (RNAi/CRISPR) to identify novel drug targets in human cancer cells.
Assist in compound screening efforts, lead optimization, and detailed biochemical and cellular characterization of hits/leads.
Develop and implement cell-based assays to measure on-target activity of lead compounds.
Culture human and mouse cancer cell lines and provide tissue culture support for animal studies.
Analyze, interpret and effectively communicate results and data to supervisor.
Maintain well-written and accurate research notebooks detailing work undertaken.
Effectively communicate ongoing work to supervisor and biology group members.

Qualifications

B.S. or M.S. in Biology or related field with 2-5 years of hands-on work experience in biotech/pharma.

Demonstrated hands-on experience with designing, executing, and analyzing cell-based mechanism of action experiments is required.
Proficiency in quantitative plate-based biochemical and cellular assays for drug discovery efforts is required (e.g. protein assay, ELISA, Cell Titer Glo, etc).
Proficiency in applying genetic methods to interrogate protein function is required (e.g. siRNA, shRNA, or CRISPR).
Experience with western blotting, qPCR, and enzyme assay development is highly desired.
Highly motivated with excellent problem solving abilities.
Flexibility to adapt to changing project needs.
Good communication, interpersonal, organizational, and leadership skills are essential.

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