Post-doctoral Fellow, Cell Biology, Drug Discovery

4 days left

Employer
Foghorn Therapeutics
Location
Cambridge, Massachusetts, US
Salary
Competitive
Posted
Jun 04, 2021
Closes
Jun 16, 2021
Ref
2151947830
Discipline
Biology
Employment Type
Fellowship
Salary Type
Salary
About Foghorn

Foghorn Therapeutics is pioneering the discovery and development of a new class of medicines targeting genetically determined dependencies within the chromatin regulatory system, an untapped opportunity for therapeutic intervention. Our proprietary Gene Traffic Control® platform gives us an integrated, mechanistic understanding of how the various components of the chromatin regulatory system interact, allowing us to identify, validate and potentially drug targets within the system. The Company, currently in pre-clinical stage, is advancing over 10 small molecule and protein degrader programs across a wide range of cancers.

Foghorn was founded in 2016 by Cigall Kadoch, Ph.D., Gerald Crabtree, M.D., and Doug Cole, M.D., of Flagship Pioneering. Learn more about Foghorn at www.foghorntx.com.

About the Chromatin Regulatory System

The chromatin regulatory system regulates gene expression by directing the movement of molecules that turn genes on and off. Disease dependencies associated with the chromatin regulatory system are estimated to impact over 2.5 million cancer patients across the United States, Europe and Japan. This system is further implicated in neurological, autoimmune, and other serious diseases.

Post-doctoral Fellow, Cell Biology, Drug Discovery

DESCRIPTION

We seek a highly motivated, creative, and collaborative researcher to join our Drug Discovery team to drive scientific projects at the interface of basic research and drug discovery. As a post-doctoral fellow at Foghorn, the candidate will have the opportunity and resources to conduct independent, cutting-edge research aimed at publication, coupled with the ability to learn about the various facets of how drugs are discovered.

WHO YOU ARE
  • PhD with a focus in biological sciences, cell biology or a related field
  • Experience with lab techniques for gene overexpression with viral vectors and gene editing (CRISPR-Cas) is required
  • Strong background in cellular and molecular biology techniques (cell culture, DNA/RNA extraction, RT-PCR, qPCR, Western Blot).
  • Ability to mine databases and analyze large genomic datasets is essential. Coding skills are considered a plus.
  • Creative problem solver and highly motivated researcher, driven to tackle challenging scientific problems as proven by a strong publication record
  • Excellent communication and inter-personal skills combined with the ability to work both independently and collaboratively.

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