NIH-NIAID-VRC-Biologist

Axle Informatics is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Overview

Axle is seeking a highly ambitious, adaptable, structured, and detail-oriented Biologist to join our vibrant team at the National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), Vaccine Research Center (VRC), Virology Laboratory (VL), Structural Biology Section (SBS) & Structural Bioinformatics Core Section (SBIS), Bethesda, MD.

Responsibilities

• Apply Antibodyomics1 pipeline (Python script; See Kwong et al. Immunological Reviews 2017) to the identification of novel broadly neutralizing antibodies, the delineation of developmental pathways of broadly neutralizing antibodies during the affinity maturation process, and the sequencing of possible somatic variants for the lineage-based characterization of B-cell responses to immunization.

• HIV-1
• Influenza
• HBV
• SARS-CoV-2
• Other emerging pathogens

Analyze and extract biological relevant information from next generation sequencing (NGS) data, and handle NGS data in NIH Short Read Archive server.Publish research results in peer-reviewed journal and presentations in scientific conferences.Prepare and share the results at laboratory-wide, NIH-wide, and national and international meetings and peer-reviewed journal publications.Serve as a Senior Project Coordinator and co-lead the Lineage-Based Vaccine Development coordination, which will align with the re-organization of the Structural Biology and Structural Bioinformatics Core Sections.Co-lead on projects, including (but not limited to) HIV-1, Malaria, Influenza and Lassa, and coordinate with scientists from other organizations or institutions involved in similar or related research projects.Design experimental approaches and provide critical evaluation for Sequencing Genomics Analysis, including deep sequencing and single cell sequence.Design informatic analysis approaches, provide critical/biological evaluation for clinical trials data, and collaborate with other scientists.Co-manage SBIS computation servers and provide support for scientific/technical research processes, including allocation of computational resources to the SBS/SBIS members to process cryoEM data and build protein atomic models.Co-manage and co-lead the integration and startup of new informatic technologies within Antibodyomics1 pipeline to support analyses, as needed, to vaccination studies, including (but not limited to) HIV-1, SARS-CoV-2, and other infectious diseases of interest at the VRC.
Experience Required / Requirements

• PhD in Biology or a related field and 5 years of postdoctoral experience.

Benefits

• 100% Medical, Dental & Vision premium coverage for Employees
• Paid Time Off (Including Holidays)
• Employee Referral Bonus
• 401K Match
• Tuition reimbursement and professional development opportunities
• Flexible Spending Accounts:
  • Healthcare (FSA)
  • Parking Reimbursement Account (PRK)
  • Dependent Care Assistant Program (DCAP)
  • Transportation Reimbursement Account (TRN)

The diversity of Axle's employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment-based age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact:

Email: careers@axleinfo.com

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individual's assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.