In Vivo Senior Research Associate, Discovery Biology

The Senior Research Associate will help drive the research and development of Sarepta's RNA therapeutic platform and programs by participating in every aspect of in vivo studies. He/she will work in a team-based laboratory environment to perform in vivo and in vitro experiments to understand disease biology and efficacy of RNA therapeutics.Primary Responsibilities include:Manage core operational activities of the vivariumPerform IV/IP/SC or ICV injections in mice, animal health monitoring, and tissue collectionsAnalyze efficacy of RNA-based therapeutics in cell and animal modelsMaintain good written records of laboratory procedures and dataInteract and communicate with study leads and other scientistsSupport day-to-day laboratory tasksEducation and skills requirements: B.S. or M.S. degree in Biology or related field with 3-5 years of relevant laboratory research experience, or the equivalent experience obtained through working in a laboratory settingExtensive experience with all aspects of animal work including mouse handling, husbandry, injection, and tissue collectionStrong technical background and experience in molecular, cellular, and in vivo biology:Pharmacological testing by different modes of delivery, functional endpoint testing, tissue collection and preparation for various analysesGene expression analysis including RT-PCR, qPCR, ddPCRProtein analysis including western blot, ELISA, and immunohistochemistryPreferred experiences:Behavioral studiesTissue culture using transformed and primary mammalian cellsAssay development and high-throughput screeningOligonucleotide researchExcellent organization and communication skills and ability to collaborate effectivelyCandidates must be authorized to work in the U.S.Sarepta Therapeutics offers a competitive compensation and benefit package.Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.PDN-9358a313-e43d-4a71-a264-f91efbb4fc8a
by Jobble