Department Of Hematopoietic Biology And Malignancy

National Institutes of Health
Ridgemont, Texas, US
May 08, 2021
May 11, 2021
Biology, Genetics
Employment Type
Salary Type
A Postdoctoral position is available in the Department of Hematopoietic Biology and Malignancy, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. This position reports to Dr. Pavan Bachireddy in the Department of Hematopoietic Biology and Malignancy.

We are seeking a talented and highly motivated Postdoctoral Fellow interested in understanding the co-evolutionary interactions between cancer and immune cells in the tumor microenvironment. Our lab uses unbiased, high-throughput technologies to decode the rules of interaction among diverse cell types in the tumor milieu that determine patient outcomes to cancer immunotherapy, primarily in hematologic malignancies. In vitro and in vivo functional genomic screens are critical approaches to validate and extend our findings.

Dr. Bachireddy is also deeply committed to the career growth and success for each member of the laboratory. Such mentorship should be intentional, planned and tailored to each member of the group - thus the laboratory operates with a primary goal of fostering career goals and development. To this end, a mentorship plan will be developed involving a senior faculty member with complementary expertise.

The fellow will lead work focused on 1) interrogation of factors reversing immune dysfunction and 2) identification of molecular and cellular determinants of successful graft-versus-leukemia outcomes, using multiple cutting-edge technologies as well as standard cell culture and immunologic approaches. Because Dr. Bachireddy is the Scientific Director of the ECLIPSE (Evolution of Cancer, Leukemia and Immunity Post Stem cEll transplant) platform, the fellow will have significant interaction and access to the vast immunogenomic and computational resources of the physically adjacent ECLIPSE platform.

We are looking for an enthusiastic, self-motivated, independent thinker with a tremendous work ethic. The position will require great planning and organizational skills. An ability to work well with others as part of a cohesive team, take initiative, and creatively problem solve are a must.

Individuals with a PhD degree in cancer biology, molecular biology, genetics, immunology, or related fields with less than 2 years of postdoctoral experience. Experiences that are desirable (but not required) include: CRISPR, next-gen sequencing (bulk or single cell genomics), or animal modeling. Candidate should have a background in immunology and the ability to prioritize and manage multiple projects. Proven track record of publications, excellent written and oral communication skills are required.

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