Biologist - NIH - VPP/VRC

4 days left

Employer
CAMRIS International
Location
Gaithersburg, Maryland, US
Salary
Competitive
Posted
May 02, 2021
Closes
May 16, 2021
Ref
2154131659
Discipline
Other
Employment Type
Full time
Salary Type
Salary
CAMRIS is a clinical and life sciences firm that realizes innovative solutions to challenges worldwide through high-quality, cost-effective program and research management services. We combine our proven systems with today's most effective, evidence-based best practices to improve the lives of people around the world. Our core practice areas include HIV/AIDS, microbiology and infectious disease research, vaccine research, development and production, global health security, biodefense, and clinical research.

CAMRIS attracts the next generation of scientists to work at premier government research and development institutions with state-of-the-art facilities and equipment, under world leaders in health research. Our exceptional benefits package that includes medical, dental and vision coverage, 401k plan with employer contribution, paid holidays, vacation, Medical and Flexible Spending Accounts, and life insurance. If you enjoy being a part of a high performing health and research organization dedicated to making the world a healthier place, please apply today!

We are seeking a Biologist to support the overall functions of the Vaccine Production Program at the National Institutes of Health (NIH).

  • Contribute to the generation of stable cell lines for vaccine and therapeutic protein candidates including monoclonal antibodies, recombinant proteins, and virus-like particles.
  • Independently execute each step of the cell line development process including plasmid production, transfection, single cell cloning, clone expansion in static culture plates and shake flasks, fed-batch analysis, and clone stability studies.
  • Use automated platforms for clone selection and screening.
  • Prepare plasmid DNA using standard molecular cloning techniques.
  • Participate in cell line development platform design, optimization, and cycle-time reduction studies including methods for clone selection, expansion, ranking, and characterization.
  • Perform small-scale process development studies using various culture vessels including tissue culture plates, shake flasks, and small-scale bioreactors.
  • Generate stable pools and perform transient protein production for supply of reagent-grade material
  • Provide laboratory support for medium preparation and ordering of supplies.
  • Maintenance of ambr15 high-throughput microbioreactor systems and associated bioprocess analyzer, coordination of service visits, and regular ordering of consumables.
  • Train other laboratory personnel on use of equipment and corresponding processes.
  • Write and review technical reports documenting process development studies and stable cell line generation work.
  • Work with other team members to generate experimental plans for process development studies.
  • Write and review standard operating procedures for cell line development processes and instrumentation.
  • Maintain complete documentation records, including a detailed and up-to-date laboratory notebook, to support regulatory filings.
  • Regularly communicate progress to team lead and present work to cell line development team.

  • B.S. in Biological Sciences with a minimum of 5 years of relevant work experience or M.S. in Biological Sciences with independent research experience in an academic or industrial setting.
  • Hands-on experience with aseptic technique and mammalian cell culture along with supporting technologies for cell line engineering including cell counting, high-throughput transfection, single-cell cloning, and flow cytometry.
  • Experience in preparing technical reports, standard operating procedures, and data presentations.
  • Ability to work independently to execute defined experiments and troubleshoot issues as needed to meet project timelines.
  • Ability to effectively communicate plans, results, challenges, and ideas to other team members in oral and written forms.
  • Familiarity with computer software for word processing and data analysis.
  • Experience in monoclonal antibody and/or vaccine production.


CAMRIS International, LLC offers competitive salaries and comprehensive benefits. Please submit your resume online at CAMRIS.com. CAMRIS is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, protected veteran status, disability status, or any other characteristic protected by any applicable federal, state, or local law.

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