Scientist II, Spatial Biology

Who We Are:

NanoString Technologies ()is a leading provider of life science tools for discovery and translational research. The company's nCounter Analysis System is used in life sciences research and has been cited in more than 3,800 peer-reviewed publications. The nCounter Analysis System offers a cost-effective way to easily profile the expression of hundreds of genes, proteins, miRNAs, or copy number variations, simultaneously with high sensitivity and precision, facilitating a wide variety of basic research and translational medicine applications. The company's GeoMx Digital Spatial Profiler enables highly-multiplexed spatial profiling of RNA and protein targets in a variety of sample types, including FFPE tissue sections. Built on pioneering principles in 2003, NanoString is blazing new trails and exploring new frontiers to adapt to the everchanging landscape and becoming smarter and more innovative in the process. We are dedicated to advancing scientific discovery and providing solutions that can have a meaningful impact in research and discovery.

Our purpose is toMap the Universe of Biology.We enable scientists to answer questions they have always wanted to ask to explore the boundaries of cellular structures and create an atlas of biological interactions that define life. We are relentless in our quest toCatalyze the Next Biological Revolutionleading toAdvancing the Human Condition. In addition to a pioneering spirit, we value:Grit. Authenticity. Ambition. Ingenuity. Customers. Join our team!

Job Summary:

NanoStringTechnologies islooking for an outstanding scientist to join ourTranslational ScienceTeamto support our new Spatial Molecular Imaging platform. Usingcutting edge technology fromNanoString,youwill applyyourunderstanding of biology to design and execute experimentstocapture the spatial proteome and transcriptome ofto uncover novel insights related tocell biology, developmental biology, cancer biology, neuroscience, and immuno-oncology.You will then communicate the results in presentations and reportswhich will lead to generation of posters, white papers, and peer reviewed publications.The work will be highlyinterdisciplinary,and you will be engaging withcell biologists, biochemists, computational biologists, and engineers. Projects willsupportbothour internal R&D groupandexternalinvestigators.

A successful candidate must be passionate aboutwet-labdriven experimentations to find innovative solutions to development hurdles.Deep understanding in diverse biology fields such as cancer biology, immunology, neuroscience, and developmental biology is preferred.Youshould be comfortable analyzingbiology at the cellular and molecular level and discussinghow this relates to health and disease. You are a good wet-lab scientist who can take an idea and quickly design an experiment that allows you to gain a better understanding of the biology.Youcancommunicate your ideas and work effectively with an interdisciplinary team and incorporate their feedback into your experimental design. You are a strategic thinker, highly motivated,proactive,and flexible in changing direction and methods. You thrive in afast-pacedenvironment, excel at managing multiple priorities, communicate clearly and get the job done.

Essential Functions:

Design and perform experiments to address specific questions in a timelymanner
Draw biological findings from large datasets
Sample preparation,library generationand data analysisfor spatial RNA-seq
Workon problems involving complex biological systems athigh-resolution
Prepare summary report for peer-reviewed publications you have authored / co-authored / contributed to
Able towork in a fast-paced and quickly changingenvironment
Ableto communicate complex ideas with an interdisciplinaryteam
Ableto work independentlyand as part of ateam
Take initiatives to conceive, design and carry-out hypothesis driven feasibility experiments to drive the development of the chemistry as well as inform the design of the hardware/software.
Drive wet-bench experimentation,subsequent data analysis/interpretation activities, and generate summaryreports
Work interactively with biophysicists, nucleic-acid chemists, fluorescence imaging specialists, and hardware/software engineers

Requirements:

Ph.D. inimmunology,immune-oncology,cancer-biology,neurobiology,cellbiology, or related field.
3~4years of industrial and/or post-doctoral work experience
Strong background in an applied biological science and single cell assays are required.
Experience with RNA and DNA sample preparation, genomics, and a wide variety of nucleic acid protocols
Strong wet bench and assay development skills
Experience withfluorescent microscopyand assays involving tissue preparations, especially FFPE (formalin fixed paraffin embedded) tissue.
Evidence of peer-reviewed publications you have authored / co-authored / contributed to
Strong understanding both theoretical and practical aspects of the experimental design
Excellent verbal and written communication skills

Additional Qualifications include:

Bioinformatics and/or wet-lab experience in single-cell RNA-seq or spatial RNA-seq assay
Experience with protein detection methodologies, proteomics, multiplexed protein assays and handling antibodies
Experience with fluorescence-based detection technologies including single moleculedetection
Experience with scripting and automation of laboratory equipment / microscopes for new assay workflow development
Experience with client management skills

NanoString is an Equal Employment Opportunity and Affirmative Action Employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender perception or identity, national origin, age, marital status, protected veteran status, or disability status. NanoString does not accept unsolicited agency resumes and will not pay fees to any third-party agency or company that it does not have a signed agreement with.

Accommodations

If you require assistance or accommodation when applying for open positions, please contact recruiting@nanostring.com.

NanoString is an Equal Employment Opportunity and Affirmative Action Employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender perception or identity, national origin, age, marital status, protected veteran status, or disability status. NanoString does not accept unsolicited agency resumes and will not pay fees to any third-party agency or company that it does not have a signed agreement with.

Accommodations

If you require assistance or accommodation when applying for open positions please contact .

Individuals seeking employment at NanoString are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation. You are being given the opportunity to provide the following information in order to help us comply with federal and state Equal Employment Opportunity/Affirmative Action record keeping, reporting, and other legal requirements.