Scientist, RNA Biology

Job Description Summary:

The Scientist, RNA Biology is responsible for planning and performing scientific experiments that contribute to PTC's research and drug discovery activities. The incumbent works cross-functionally with internal departments, and external resources as appropriate, as part of PTC's discovery science project teams.
The Scientist, RNA Biology supports adherence to relevant regulatory requirements and company Standard Operating Procedures (SOPs) as appropriate.

Job Description:

Primary duties/responsibilities:

• With guidance from the advisor plans, initiates, directs and executes scientific research and experiments and interprets and communicates results as part of multi-disciplinary team(s). This includes performing analyses of primary research literature.
  
• Presents findings internally to cross-functional teams.
  
• May Participate in the development and writing of patent applications
  
• Abides by all safety and regulatory guidelines.
  
• Maintains a detailed laboratory notebook.
  
• Performs other tasks as assigned
  
• Interviews and contributes to the evaluation of candidates.
  
• May provide scientific advice to research leadership on projects and areas of expertise.
  
• Abides by all safety requirements.
  
• Contributes to general lab needs such as:
  
  • Equipment maintenance.
    
  • Capital equipment purchases.
    
  • Troubleshoot
    

KNOWLEDGE/SKILLS/ABILITIES REQUIRED

• Hands on experience with mammalian cell culture.
  
• Experience in nucleic acid, isolation, quantification.
  
• Experience in protein quantification end analysis methods such as Western blot, ELISA, MSD.
  

* Minimum level of education and years of relevant work experience.

• Ph.D. in a scientific discipline preferably Molecular Biology with atleast 1-2 years' post-doctoral or Industry experience
  

* Special knowledge or skills needed and/or licenses or certificates required.

• Demonstrate ability to work on complex problems to produce experimental data across one or more projects.
  
• Exercises independent judgement within defined procedures and practices.
  
• Demonstrates technical proficiency, collaboration with others within a fast-paced, matrixed, team environment consisting of internal and external team members.
  
• Possesses detailed and expert knowledge of scientific principles and concepts.
  
• Demonstrate ability to work effectively in a multi-disciplinary team environment.
  
• Proficiency with Microsoft Office preferably MS Excel and MS PowerPoint or similar
  
• Excellent verbal and written communication and skills.
  
• Analytical thinker with excellent problem-solving skills.
  
• Demonstrates an understanding of the strategic alignment of his/her work with corporate goal(s) and demonstrates the ability to adapt to changing priorities and deadlines.
  
• Excellent planning, organization and time management skills including the ability to support and prioritize multiple projects.
  

*Special knowledge or skills and/or licenses or certificates preferred.

• Demonstrated knowledge and understanding of RNA biology with an emphasis on pre-mRNA splicing and translational control of gene expression.
  
• Experience designing and conducting cell-based studies of compound activity on pre-mRNA splicing as well as mechanism of action studies.
  
• Hands-on experience with bioinformatics tools, and next-generation sequencing.
  

* Travel requirements

Up to 10%

*Physical requirements (only note if the job requires physical capacity beyond general office work)

Office/Laboratory based position

EEO Statement:

PTC Therapeutics is an equal opportunity employer. We welcome applications from all individuals, regardless of race, color, national origin, gender, age, physical characteristics, social origin, disability, religion, family status, pregnancy, sexual orientation, gender identity, gender expression, disability, veteran status or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.

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