Senior Scientist - Chemical Biology

Job Description
Become part of cutting edge and highly innovative Chemical Biology and Quantitative Biosciences departments. Using robust scientific methodology, novel translational models, and state-of-the-art instrumentation and automation, we collaborate to discover the next medical breakthrough. To achieve our goal, we have added new capability enhancements for higher-resolution interrogation of novel biology and the molecular mechanism of action of molecules that help advance the best drug candidates into the clinic.
Target discovery is critical to the success of drug discovery. We are therefore seeking an innovative cell biologist to join the Chemical Biology group at our company's Research Laboratories in Boston/Cambridge to help us in this endeavor.
- Become part of a creative and flexible team; collaborate, manage and work closely with other scientists. Contribute to project strategy, experimental design, analysis, and interpretation of experiments
- Collaborate with Oncology, Metabolic Disease, Neuroscience and Infectious Disease discovery teams to develop and execute on phenotypic screening strategy
- Have a proven track record across cell biology and imaging projects
- Have a good understanding of biological concepts and phenotypic screening workflows
- Possess strong analytical skills
- Function and communicate effectively in a highly productive multi-disciplinary environment
Preferred Experience and Skills
- A background in cell-based assay development and familiarity with imaging-based approaches to interrogate compound effects on phenotypes of interest is required
- The successful candidate will be able to design cell-based experiments using genetic and pharmacological manipulation of pathways and proteins in relevant cell systems to validate novel targets and characterize molecular mode of action of tool molecules
- A track record of achievement in independently designing and executing experiments is required
- Preference will be given to candidates with a background in chemical biology, or experience in 3D cellular culture or automation of cellular assays
- Excellent attention to detail and strong communication (oral and written) skills
- Highly self-motivated and capable of prioritizing deliverables among multiple simultaneous projects
- Ability to build strong relationships within highly collaborative, multidisciplinary teams to effectively drive early drug discovery initiatives
Qualifications/Education
- Ph. D. in Biology or related field or M.S. with 3+ years of experience or B.S. with 5+ years of working experience in a pharma, biotech or academic setting
We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we "follow the science" that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.
Who we are ...
We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.
What we look for ...
In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth .
INVENT.
IMPACT.
INSPIRE.
NOTICE FOR INTERNAL APPLICANTS
In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
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Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
Regular
Relocation:
Domestic/International
VISA Sponsorship:
Yes
Travel Requirements:
Flexible Work Arrangements:
Shift:
Valid Driving License:
Hazardous Material(s):
Number of Openings:
1
Requisition ID: R102488