4 days left

Synectics Inc.
Worcester County, Massachusetts, US
Apr 28, 2021
May 21, 2021
Employment Type
Full time
Salary Type
Job Description
Involved with all aspects of protein purification and protein chemistry to support biopharmaceutical process development.
Execute high through put scale down robotic purification from ear006Cy stage to late stage for cross function groups, viral clearance, process characterization, and continuous process improvement studies, performing basic data acquisition and analysis, documenting in electric lab notebooks
Develop economical, robust steps for recovering the target protein from bioreactor harvests using chromatography, filtration, and other separation techniques
Developing downstream purification processes to be transferred to Manufacturing and performing laboratory scale process characterization studies.
Perform various bioanalytical assays, including HPLC, ELISAs and SDS-PAGE, to aid in rapid process development.
Supply technical support for pilot and/or GMP manufacturing of clinical materials.

BS Degree in Chemical or Biochemical engineering, biochemistry or biology with 0-5+ years of work experience; OR
MS Degree with 0-2+ years of work experience
Basic knowledge of protein purification and standard analytical techniques
Must possess strong written, oral, and collaborative skills in order to effectively communicate experimental procedures and results.
Basic biological scientific understanding
Enjoy calculating, making chemical solutions and pipetting
Good English: written and oral for effective communication
Understanding of characterization (UV, SDS-PAGE, HPLC analytical), chromatography, filtration and separation technics
Ability to work well with others.
Laboratory experience with purification unit operations and techniques, biological assays
Experience with scale down robotic Robocolumn chromatography in a fasted paced high through put setting.
Experience with a Akta chromatography and Tecan or similar robotics purification is preferred.

Company DescriptionSynectics is one of the nation's foremost consulting firms, working with a client base that includes some of the leading institutions and Fortune 500 corporations in the United States. We seek to bring the most highly qualified professionals to assignments that they will find challenging and fulfilling. We also seek to justify our clients' expectations that every Synectics consultant will bring the highest possible effort to their endeavors every day. Our success has depended on our consistent ability to achieve both of these goals.

Synectics serves an extremely diverse client base which represents an equally diverse range of industries and institutions. The technologies we support have always been responsive to this extremely broad spectrum. In order to fully engage with this continually changing commercial and technological landscape, our employees must draw on their own varying interests, skills and backgrounds. This insight, reflected in our daily practices, has always been our fundamental strength as a company, and it continues to serve us well in all our efforts.

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