Senior Scientist - Cancer Biology

4 days left

Talus Bioscience
Seattle, Washington, US
Apr 28, 2021
May 18, 2021
Biology, Statistics
Employment Type
Full time
Salary Type
Talus Bio is an early-stage drug discovery company located in Seattle, WA that worksto discover and develop cutting-edge therapeutics for gene regulation.

Role Description
We are seeking a Senior Scientist to join our team in a full-time role. The Senior Scientist will work as part of a small team to deploy our platform to enable drug discovery for gene regulators. We are looking for a scientific leader interested in solving complex biological problems in a fast-paced, innovative, early-stage biotech environment.

  • Design and execution of experiments to discover, validate and understand the mechanism of action for small molecule therapeutics
  • Protein isolation from mammalian cells and peptide preparation for mass spectrometry
  • Design, execution and analysis of genomics, epigenomics and/or transcriptomics experiments
  • Data analysis using bioinformatics software including R and/or Python
  • Conduct independent research and demonstrate scientific leadership within the project team and across departments; Collaborate with all the functions within and outside of Talus to advance our science
  • Accurately document experiments and results in electronic laboratory notebooks in a timely fashion
  • Maintain a safe and productive laboratory environment
  • Prepare and present experimental results, analysis, and plans in R&D meetings

  • The successful candidate will have a PhD with 0-3 or BS/MS degree with 5-7 years of industry experience in pharmaceutical development
  • Familiarity with biochemical and cell-based assay development
  • Familiarity with modern sequencing-based assays including ChIP-seq, ATAC-seq and RNA-seq
  • Strong skills in statistics and data analysis using bioinformatics software including R and/or Python
  • Ability to deliver complex results to teams of diverse scientific backgrounds
  • Ability to work effectively and collaboratively on cross-functional projects teams
  • Excellent oral, presentation, and written communication skills

  • Experience working with shotgun proteomics data
  • Experience with CRISPR or related genome-editing technologies
  • Deep familiarity with cancer biology
  • Experience working in small teams and managing contract research organizations (CROs)

COVID Precautions

We value the safety of our employees and have put in measures to reduce the risk of COVID that include:
  • Remote interview process
  • Personal protective equipment provided and required
  • Social distancing guidelines in place

Employees will be required to receive twice-weekly free COVID testing and will be notified if other employees in our lab space tests positive.

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