Principal Research Associate/Senior Research Associate, Molecular and Cellular Biology

Employer
Calico Labs
Location
San Francisco, California, US
Salary
Competitive
Posted
Apr 28, 2021
Closes
May 11, 2021
Ref
2145266909
Discipline
Biology
Employment Type
Full time
Salary Type
Salary
Position description:

Calico is inviting applications from exceptional biologists who are excited to work within a fast-moving scientific team exploring signaling stress pathways in support of translational efforts. The selected candidate will fill a hands-on wet lab position and will be expected to design and execute studies under the supervision of the principal investigator. He/she will be detail-oriented, organized, adaptable and self-motivated. The successful candidate must be an experienced experimentalist and be very comfortable presenting results to cross-functional teams. Level of appointment will be commensurate with experience.

Responsibilities:

Execute established molecular biology and mammalian cell culture protocols
Develop and optimize fit-for-purpose assays to interrogate mechanisms that further our understanding of relevant biology
Analyze and interpret data, delivering results for time-sensitive goals
Take ownership of project and work as part of a collaborative team
Requirements:

BS/MS with 5+ years of technical experience
Mastery of: Mammalian cell culture including primary cells and/or 3D-cultures, iPSCs maintenance and differentiation, molecular biology (PCR, Gibson assembly, DNA/RNA isolation), biochemistry (SDS-PAGE, Western Blot)
Experience with: Fluorescence microscopy, immunohistochemistry, flow cytometry (fixed- and live-cell), protein purification and assay development, 96- and 384-well microplate-based assays using recombinant proteins and/or cells
Strong attention to detail, possess quantitative skills and excellent verbal/written communication skills
Able to plan, execute and troubleshoot experiments independently

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